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Stimuli-Responsive Polymers

Navid Rabiee


Nanogels are three-dimensional nanosized networks that are formed by physically or chemically cross-linking polymers. They have been explored as a drug-delivery system due to their biocompatibility, high stability, particle-size adjustment, drug-loading capability and modification of the surface for active targeting by cognate receptors on the target cells of tissues. Nanogels can respond to stimuli such as pH, temperature, light and redox, which results in the controlled release of drugs and targeting of site by environmental stimuli and prevents accumulation in non-target tissues, minimizing the side effects of the drug. This book aims to provide a general introduction to nanogels and the design of various stimuli-sensitive nanogels that can control drug release in response to specific stimuli.

About Editors

Navid Rabiee received his MSc in inorganic chemistry from Shahid Beheshti University, Iran, in 2018. In 2017, he joined ANNRG to collaborate with Mahdi Karimi's research lab at Iran University of Medical Science. 

Mohammad Rabiee is an associated professor at the Biomedical Engineering Department of Amirkabir University of Technology, Iran. 

Mojtaba Bagherzadeh is a professor at the Department of Chemistry at Sharif University of Technology, Iran. 

Michael R Hamblin is a principal investigator at the Wellman Center for Photomedicine, Massachusetts General Hospital, and an associate professor at Harvard Medical School.

Table of Contents

Chapter 1            

Stimuli- Responsive Polymers: Introduction       

Chapter 2           

Stimuli-Responsive Polymers: Synthesis Approach           

2.1. Physical self-assembly of interactive polymers           

2.2. Polymerization of polymers in a heterogeneous environment           

Chapter 3           

Stimuli-Responsive Polymers: Biomedical Concepts         

3. Stimulus-responsive nanogels

3.1. pH-responsive nanogels     

3.2. Temperature-responsive nanogels 

3.3. Redox-responsive polymers

3.4. Light-responsive polymers 

3.5. Multi-stimuli responsive polymers 

3.5.1. pH/Temperature dual-responsive polymers           

3.5.2. pH/ Redox dual -responsive polymers       

Chapter 4           

Stimuli-Responsive Polymers: Recent Advances

Chapter 5           

Stimuli-Responsive Polymers: Future Perspectives           


Paperback ISBN: 9780750329903

Ebook ISBN: 9781643276373

DOI: 10.1088/2053-2571/ab1342

Publisher: Morgan & Claypool Publishers

Series: Series in Photomedicine and Biophotonics


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