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Nanoparticle (NP)-Based Delivery Vehicles

Navid Rabiee, Mahsa Kiani, Mojtaba Bagherzadeh, Mohammad Rabiee, Sepideh Ahmadi

Description

Gene therapy as a potential method for the treatment of genetic disorders and other malignancies, as well as the treatment of many cancers, has attracted a great amount of attention in recent years. Current research focuses on stable and smart drug/gene-delivery systems, including controlled release. Nanoparticle (NP)-Based Delivery Vehicles looks at smart nanostructures and how these are considered a promising approach when applied to drug- and gene-delivery systems, in addition to how to solve the problems related to the inefficient transfer of medication to the affected cells.

About Editors

Navid Rabiee graduated with an MSc in inorganic chemistry from Shahid Beheshti University, Iran, in 2018. He has also worked on drug-delivery systems based on biocompatible and biodegradable polymers associated with different types of the sensitizers, especially porphyrins, under the supervision of Mohammad Rabiee at Amirkabir University of Technology, in Iran.

Mahsa Kiani graduated with an MSc in inorganic chemistry from Isfahan University of Technology, Iran, in 2015. In 2019, she joined ANNRG to collaborate with Mahdi Karimi's research lab at Iran University of Medical Science, in Iran.

Mojtaba Bagherzadeh is a professor at the Department of Chemistry of Sharif University of Technology, Iran. His current research interests include inorganic chemistry, inorganic catalysis and bio-inorganic chemistry.

Mohammad Rabiee is an associate professor at the Biomedical Engineering Department of Amirkabir University of Technology, Iran. His current research interests include smart drug-delivery systems, tissue engineering and biological sensors.

Spideh Ahmadi received her BSc in biology from Lorestan University, in 2011, and her MSc in molecular genetics from Zabol University, Iran, in 2014. She is currently working on smart nanostructures applied in therapeutic agent delivery systems employed for the diagnosis and therapy of various diseases.

Table of Contents

Contents

Chapter 1           

An introduction to Drug/Gene Delivery Systems

Chapter 2           

Smart nanostructures   

Controlled gene delivery system: The concept   

Chapter 3

Aptamer-based nanostructures

Aptamer-conjugated nanoparticles

Chapter 4

Protein-based nanostructures I 

Gelatin

Gelatin synthesis approaches   

Gelatin based nanocarriers         

Chapter 5           

Protein-based nanostructures II

Elastin 

Elastin synthesis approaches     

Elastin based nanocarriers         

Chapter 6           

Protein-based nanostructures III             

Silk synthesis approaches           

Silk based nanocarriers 

Chapter 7           

Strategic approach: toward the futures 

Bibliographic

Paperback ISBN: 9780750329750

Ebook ISBN: 9781643274515

DOI: 10.1088/2053-2571/ab01f6

Publisher: Morgan & Claypool Publishers

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