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Antimicrobial Photodynamic Inactivation and Antitumor Photodynamic Therapy with Fullerenes

Lucas F de Freitas, Michael R Hamblin


This book provides detailed and current information on using fullerenes (bucky-balls) in photodynamic therapy (PDT), one of the most actively studied applications of photonic science in healthcare. This will serve as a useful source for researchers working in photomedicine and nanomedicine, especially those who are investigating PDT for cancer treatment and infectious disease treatment. The book runs the gamut from an introduction to the history and chemistry of fullerenes and some basic photochemistry, to the application of fullerenes as photosensitizers for cancer and antimicrobial inactivation.

About Editors

Lucas F de Freitas received his PhD in bioengineering from the University of São Paulo, Brazil (2016). Part of his PhD research was done under supervision from Dr Hamblin. He has publications in the biomedical field, especially on light interaction with microorganisms and with the human body. Michael Hamblin is a Principal Investigator at the Wellman Center for Photomedicine, Massachusetts General Hospital, an Associate Professor of Dermatology, Harvard Medical School and affiliated faculty at Harvard-MIT Division of Health and Science Technology.

Table of Contents

Table of Contents: Introcuction / Fullerenes / Resonant energy transfer / Photo-induced charge-transfer / Fullerenes as photosynthesizers / Chemical modifications / Examples of the synthesis of monocationic and polycationic / Photodynamic therapy / Photosensitizer formulations for fullerene-mediated PDT / In vitro anti-cancer PDT with fullerenes / In vivo PDT for cancer / Antibiotic resistance and viral infections / general aspects of photodynamic inactivation of bacteria / In vitro antimicrobial PDT with fullerenes / In vivo antimicrobial PDT with fullerenes / Conclusions


Paperback ISBN: 9780750328210

Ebook ISBN: 9781681740553

DOI: 10.1088/978-1-6817-4247-2

Publisher: Morgan & Claypool Publishers


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